Welcome to Jean-michel Arbona's webpage

Welcome to this webpage, mainly about the incredible physics of DNA!

DNA Replication, study with neural network tools

In this ongoing project at the ENS de lyon, in collaboration with the team of Olivier Hyrien at the ENS at the ibens with Magali Hennion we study replication by using neural network on output of Oxford nanopores

DNA Replication

In this ongoing project at the ENS de lyon, in collaboration with the team of Olivier Hyrien at the ENS at the ibens and Arach goldar at the CEA saclay and Alain Arneodo and Francoise Argoul at the LOMA bordeaux we study the temporal dynamics and the spatio temporal dynamics of the replication

Structure of Yeast Nucleus and DNA repair mechanism

In this project at the Pasteur Institute in the team of Cristophe Zimmer, we studied the structure on the chromosomes, by exploring through molecular dynamics modeling, the structural parameters of the chromation fiber that allowed to reproduce conformation capture experiments and static and live distance measurement from microscope imaging

DNA Origami

In this work done during my PhD under with Jean-Pierre Aimé and Juan Elezgaray we studied a very funny biophisical object: tho DNA Origami. We studied its mechanical and thermodynamical properties.

1.
Ruiz, I. M. et al. Connecting localized DNA strand displacement reactions. Nanoscale 7, 12970–12978 (2015).
2.
Arbona, J.-M., Aimé, J.-P. & Elezgaray, J. Cooperativity in the annealing of DNA origamis. The Journal of chemical physics 138, 01B606 (2013).
3.
Song, J. et al. Direct visualization of transient thermal response of a DNA origami. Journal of the American Chemical Society 134, 9844–9847 (2012).
4.
Arbona, J.-M., Aimé, J.-P. & Elezgaray, J. Folding of DNA origamis. Frontiers in Life Science 6, 11–18 (2012).
5.
Arbona, J. M., Aimé, J.-P. & Elezgaray, J. Folding of small origamis. The Journal of chemical physics 136, 02B605 (2012).
6.
Renˇciuk, D., Sugiyama, H., Arbona, J.-M., Aimé, J.-P. & Mergny, J.-L. Guided Assembly of Tetramolecular GQuadruplexes. (2013).
7.
Yatsunyk, L. A. et al. Guided assembly of tetramolecular G-quadruplexes. ACS nano 7, 5701–5710 (2013).
8.
Wong, H., Arbona, J.-M. & Zimmer, C. How to build a yeast nucleus. Nucleus 4, 361–366 (2013).
9.
Arbona, J.-M., Herbert, S., Fabre, E. & Zimmer, C. Inferring the physical properties of yeast chromatin through Bayesian analysis of whole nucleus simulations. Genome Biology 18, 81 (2017).
10.
Arbona, J. M., Aimé, J.-P. & Elezgaray, J. Modeling the mechanical properties of DNA nanostructures. Physical Review E 86, 051912 (2012).
11.
Arbona, J.-M., Elezgaray, J. & Aimé, J.-P. Modelling the folding of DNA origami. EPL (Europhysics Letters) 100, 28006 (2012).
12.
Arbona, J.-M. Origami d’ADN: étude des propriétés mécaniques et du processus de formation. (Bordeaux 1, 2012).